Alexis Kirkendall passed her comprehensive exam and advances to candidacy!!

Congratulations to Alexis Kirkendall, PhD candidate in the Microbiology Program, for passing her comprehensive exam!! The exam involved writing a research proposal on a topic outside of her main focus, and presenting her idea for an hour to her faculty committee, who then asked detailed questions about her work and understanding of this research for almost two hours.

Over the next two or three years, her dissertation research will focus on culturing bacteria that we previously isolated from mice consuming a steamed broccoli sprout diet, to test their capacity to grow amongst the gut pathogen Helicobacter pylori and produce the anti-inflammatory sulforphane under different conditions, as well as which bacteria produce sulforaphane in the gut, how they do it, and under which circumstances. It complements the collective lab research on how broccoli sprouts and gut microbes can be used to resolve Inflammatory Bowel Disease.

Alexis Kirkendall

Doctor of Philosophy candidate, Microbiology

Alexis is from Ohio and initially joined the lab in 2022 when she was majoring in Biology at Heidelberg University, through the Summer 2022 REU, during which she divided her time researching Cryptosporidium in cows, helping in the MSE Symposium, and aiding in the Camel Rumen Microbiome Project. Alexis continued her work remotely, and returned to Maine in summer 2023 as a research assistant for several projects related to gut microbes, diet, and Inflammatory Bowel Disease. Her research interests are in genetics and she has a love for the fascinating world of microbes.

She returned in January 2024 as a graduate student in the Microbiology program!

 

Lola Holcomb won a student research award from the Bioscience Association of Maine!!

Congratulations to Lola Holcomb, PhD candidate in the Graduate School for Biomedical Sciences and Engineering program, for winning a graduate student research award from the Bioscience Association of Maine!!

Over the next few months, she’ll focus on characterizing candidate anti-inflammatory bacterial species and genes of the gut microbiome, using whole genome sequence data from bacteria we previously isolated during a broccoli sprout diet study. This is part of Lola’s larger PhD project investigating which bacteria produce sulforphane in the gut, how they do it, and under which circumstances. It complements the collective lab research on how broccoli sprouts and gut microbes can be used to resolve Inflammatory Bowel Disease.

Portrait of Lola Holcomb, wearing a block sweater on a beach at sunset

Lola Holcomb, B.S.

Doctorate of Philosophy candidate, Biomedical Science

Lola entered as a rotating first-year GSBSE student in March 2022, and declared the Ishaq Lab her dissertation lab soon after.  Troubled with indecisiveness and the desire to research, well, everything, she quickly found that using bioinformatics and big data as a lens to study microbial ecology (and in time, its relation to social equity) allowed her to do the kind of meaningful interdisciplinary research she’s always wanted to do.  Lola is currently working on 16s data analysis for other ongoing lab projects, comparing gut microbiomes of mouse models of Inflammatory Bowel Disease with broccoli as a dietary treatment.  Lola is currently doing 16S data analysis for ongoing lab projects and developing a metagenomic analysis workflow to compare gut microbiomes of mouse models of Inflammatory Bowel Disease with broccoli as a dietary treatment. In addition to research, she instructs a graduate-level Genetics course, tutors several Biology undergraduate students, and serves as a GSBSE senator in the Graduate Student Government here at UMaine. 

Google Scholar page.

Alexis Kirkendall won a student research award from the Bioscience Association of Maine!!

Congratulations to Alexis Kirkendall, PhD student in the Microbiology Program, for winning a graduate student research award from the Bioscience Association of Maine!!

Over the next year, she’ll focus on culturing bacteria that we previously isolated from mice consuming a steamed broccoli sprout diet, to test their capacity to grow amongst the gut pathogen Helicobacter pylori and produce the anti-inflammatory sulforphane under different conditions. This will be part of Alexis’ larger PhD project investigating which bacteria produce sulforaphane in the gut, how they do it, and under which circumstances. It complements the collective lab research on how broccoli sprouts and gut microbes can be used to resolve Inflammatory Bowel Disease.

Alexis Kirkendall

Doctor of Philosophy student, Microbiology

Alexis is from Ohio and initially joined the lab in 2022 when she was majoring in Biology at Heidelberg University, through the Summer 2022 REU, during which she divided her time researching Cryptosporidium in cows, helping in the MSE Symposium, and aiding in the Camel Rumen Microbiome Project. Alexis continued her work remotely, and returned to Maine in summer 2023 as a research assistant for several projects related to gut microbes, diet, and Inflammatory Bowel Disease. Her research interests are in genetics and she has a love for the fascinating world of microbes.

She returned in January 2024 as a graduate student in the Microbiology program!

 

Upcoming talk at the 9th Southern California Microbiome Symposium in September!

I’m ecstatic to be heading back to southern California this September to present at the 9th annual Southern California Microbiome Symposium. I’ll be sharing my work on microbes and social equity, especially as pertains to food systems and sustainability. Registration is free, and can be found here.